One of the most important quality control methods used in the pharmaceutical, chemical, cosmetics, food and beverage industry is polarimetry – optically active substances are analysed by determining their angle of rotation. The angle of rotation allows you to ascertain the identity and quality of substances as well as their concentration in mix tures. It can also indicate the progress of reactions and conversions. Polarimeters are used in a wide range of applications – from the determination of the purity and concentration of ingredients in pharmaceuticals to the maturity testing of agri cultural products to the measurement of the sugar
con tent in beverages and candies.

The high-speed polarimeters of the Professional series are the fastest in the world – thanks to A.Krüss patented measure ment procedure, which reduces the measurement time to approx. 1 s regardless of the sample’s angle of rotation. They achieve a high measure ment accuracy of up to ±0.002°, offer the option of a water bath or Peltier temperature control as well as an automatic operation and feature all the functions that are important in FDA-regulated sectors. Their self-explanatory, well-arranged user interface ensures a convenient user experience.

Typical Applications

Polarimeters can be used for a variety of applications in the
pharmaceutical, chemical, sugar, food and beverage industry,
as well as for the production of flavors and fragrances.

• Determination of the concentration of sugar as an ingredient
  of pharmaceutical agents
• Purity control and content determination
• Determination of the stereochemical composition
  and mutarotation
• Determination of concentrations in raw materials,
  preliminary, intermediate and end products
• Determination of sugar concentration
• Characterisation of new synthetic substances
• Purity control and concentration determination
• Monitoring of chemical processes during the production of
  optically active substances
• Characterisation tests in research laboratories
• Reaction kinetic analyses

Polarimeter P8000-T with circulating thermostat PT80

The polarimeter models P8000-T and P8100-T will allow for a
circulation thermostat temperature control in the range between
8 °C and 40 °C when combined with temperature controlled measurement
tubes and a thermostat. That makes them suitable for high-precision
measurements in quality control. Especially if a multitude of different
temperature controlled measurement tubes are to be used, the P8000-T
and P8100-T are the right choice. We offer a very large selection of
this type of tubes.

• Temperature measurement directly inside the sample
• Accurate, homogeneous water bath temperature control
• Large selection of temperature-controlled measurement tubes
• Quick coupling system for an easy measurement tube change
• Highest accuracy over the entire measurement range
• Very short measurement time of approx. 1 s
• Measurement up to an optical density of 3.0 OD
• Intuitive operation via touch-screen display
• Predefined scales (opt. rotation, spec. rotation, int. sugar scale,
  concentration)
• Any number of freely definable scales with conversions based
  on tables or formulas
• Chemical-resistant materials
• Compliance with GMP/GLP, 21 CFR Part 11, Pharmacopeia (USP,
  BP, JP, Ph. Eur.), FDA, ISO, HACCP, OIML, ASTM, ICUMSA, NIST

Polarimeter P8000 with measurement tube PRG-100-E and temperature sensor PRT-E

The polarimeter models P8000 and P8100 are the right choice for all
applications where sample temperature control for high-precision
measurements is not absolutely necessary. The devices are suitable for
nearly all samples as the parts that come in contact with the sample are
chemical resistant. The P8000 and P8100 are recommended for all
basic applications. Instead of a temperature control, the temperature
can be compensated according to ICUMSA. That allows you to take
measurements at any temperature; the results will then be converted to
the desired temperature. In addition, the international sugar scale has
been predefined on our devices, and the initial weight is taken into
account for the conversion into the specific rotation.

• Suitable measurement tubes for any type of sample
• Temperature measurement directly inside the sample
• Reliable temperature compensation
• Highest accuracy over the entire measurement range
• Very short measurement time of approx. 1 s
• Measurement up to an optical density of 3.0 OD
• Intuitive operation via touch-screen display
• Predefined scales (opt. rotation, spec. rotation, int. sugar scale,
  concentration)
• Any number of freely definable scales with conversions based on
  tables or formulas
• Chemical-resistant materials
• Compliance with GMP/GLP, 21 CFR Part 11, Pharmakopöen (USP,
  BP, JP), FDA, ISO, HACCP, OIML, ASTM, ICUMSA, NIST

See leaflet for more details.